Distal upper limb involvement in myasthenia-myositis association.

Antonio LaulettaLaura FiondaGioia MerlonghiLuca LeonardiStefania MorinoElisabetta BucciLaura TufanoGirolamo AlfieriRocco CostanzoElena RossiniMarco SalvettiGiovanni AntoniniMatteo Garibaldi

Published in: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology (2022)

We provide the histopathological evidence of a prominent inflammatory process responsible of distal upper limb weakness in MG-IM association. Muscle biopsy does not reveal any typical histopathological feature of other nosologically definite inflammatory myopathy, leading MG-IM association to come close to the group of overlap-myositis (OM) with the myopathological features of non-specific myositis (NSM).

Keyphrases

upper limb
interstitial lung disease
oxidative stress
machine learning
skeletal muscle
late onset
systemic sclerosis
genome wide
single cell
deep learning
dna methylation
early onset
idiopathic pulmonary fibrosis