Adherence to low-dose methotrexate in children with juvenile idiopathic arthritis using a sensitive methotrexate assay.
Julia E MöhlmannSytze de RoockAnnelies C EgasEvelien Ter WeijdenMartijn J H DoelemanAlwin D R HuitemaMatthijs van LuinJoost F SwartPublished in: Pediatric rheumatology online journal (2024)
Quantification of MTX in plasma is a feasible and objective method to assess adherence in patients using low-dose weekly MTX. In clinical practice, the use of this method could be a helpful tool for physicians to refute or support suspicion of non-adherence to MTX therapy.
Keyphrases
- low dose
- high dose
- juvenile idiopathic arthritis
- end stage renal disease
- clinical practice
- newly diagnosed
- ejection fraction
- chronic kidney disease
- primary care
- peritoneal dialysis
- glycemic control
- high throughput
- prognostic factors
- type diabetes
- stem cells
- mesenchymal stem cells
- bone marrow
- metabolic syndrome
- insulin resistance