Pancreatic Enzyme Use Reduces Pancreatitis Frequency in Children With Acute Recurrent or Chronic Pancreatitis: A Report From INSPPIRE.

Alvin Jay Freeman Kenneth Ng Fuchenchu WangMaisam A Abu-El-HaijaAnkur Chugh Gretchen A CressDouglas S FishmanCheryl E Gariepy Matthew J GieferPraveen GodayTanja Y GonskaAmit S Grover Douglas Lindblad Quin Y Liu Asim Maqbool Jacob A MarkBrian A McFerronMegha S MehtaVeronique D MorinvilleRobert A Noel Chee Yee OoiEmily R PeritoSarah Jane Schwarzenberg Zachary M SellersMichael WilschanskiYuhua Zheng Ying Yuan Dana K Andersen Mark E Lowe Aliye Ucnull null

Published in: The American journal of gastroenterology (2024)

In a retrospective analysis, use of PERT was associated with a reduction in the incidence rate of AP among children with pancreatic-sufficient ARP or CP. These results support the need for a clinical trial to evaluate the efficacy of PERT to improve clinical outcomes among children with ARP or CP.

Keyphrases

clinical trial
young adults
risk factors
study protocol
phase ii