Investigating the origin and evolution of cerebral small vessel disease: The RUN DMC - InTENse study.
Annemieke Ter TelgteKim WiegertjesAnil M TuladharMarlies P NozJosé P MarquesBenno GesierichMathias HuebnerHenk-Jan Mm MutsaertsSuzette E Elias-SmaleMarie-José BeelenStefan RopeleRoy Pc KesselsNiels P RiksenCatharina Jm KlijnDavid G NorrisMarco DueringFrank-Erik de LeeuwPublished in: European stroke journal (2018)
Our study will provide a better understanding of the role of DWI+ lesions in the pathophysiology of SVD and will further unravel the structural and functional consequences and clinical importance of these lesions, with an unprecedented temporal resolution. Understanding the role of acute, potentially ischaemic, processes in SVD may provide new strategies for therapies.