B-cell lymphoma-2-associated transcription factor 1 is overexpressed and contributes to sorafenib resistance in hepatocellular carcinoma.

Shijun YuXiao WangNing DouJun ZhouYong GaoYandong Li

Published in: Hepatology research : the official journal of the Japan Society of Hepatology (2019)

BCLAF1 is a potential oncogene in HCC by inducing autophagy to maintain tumor cell growth in response to stress conditions, and it could serve as a potential biomarker for predicting the prognosis of HCC patients and screening patients who are suitable for sorafenib therapy.

Keyphrases

end stage renal disease
transcription factor
newly diagnosed
chronic kidney disease
peritoneal dialysis
mesenchymal stem cells
diffuse large b cell lymphoma
human health