Primary Ewing's sarcoma of the talus.
Prabodh KantiwalSandeep Kumar YadavAasma NalwaRajesh Kumar RajnishPublished in: BMJ case reports (2023)
Ewing's sarcoma is a malignant round cell tumour of bones and soft tissues that usually arises from the diaphyseal or meta-diaphyseal parts of long bones and less commonly from flat bones. It occurs rarely in the foot and if occurs, the calcaneus and the metatarsals are commonly involved. We present a case of a young woman diagnosed with primary Ewing's sarcoma of the talus with local spread to adjacent tarsals and the ankle joint. Ewing's sarcoma of feet, if present with even a trivial suspicion of spread either locally or distant, makes limb salvage surgery difficult. So, the treatment with radical surgery or by combined chemotherapy and radiotherapy should be considered-keeping in mind the complex anatomy of the foot and the difficulty in achieving tumour-free margins. Based on this experience, she underwent below-knee amputation. The patient received adjuvant chemotherapy and survived with a disease-free survival at the latest follow-up of 1 year.
Keyphrases
- free survival
- minimally invasive
- coronary artery bypass
- case report
- locally advanced
- radiation therapy
- single cell
- gene expression
- total knee arthroplasty
- lymph node
- stem cells
- surgical site infection
- cell therapy
- mesenchymal stem cells
- coronary artery disease
- knee osteoarthritis
- bone marrow
- middle aged
- rectal cancer
- replacement therapy
- combination therapy