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G-CSF secreted by mutant IDH1 glioma stem cells abolishes myeloid cell immunosuppression and enhances the efficacy of immunotherapy.

Mahmoud S AlghamriBrandon L McClellanRuthvik P AvvariRohit ThallaStephen V CarneyMargaret S HartlageSantiago HaaseMaria VentosaAyman TaherNeha KamranLi ZhangSyed Mohd FaisalFelipe J NúñezMaría Belén Garcia-FabianiWajd N Al-HolouDaniel A OrringerShawn L Hervey-JumperJason HethParag G PatilKaren EddySofia Diana MerajverPeter J UlintzJoshua D WelchChao GaoJialin LiuGabriel NuñezDolores HambardzumyanPedro R LowensteinMaria Graciela Castro
Published in: Science advances (2021)
[Figure: see text].
Keyphrases
  • stem cells
  • cell therapy
  • wild type
  • single cell
  • bone marrow
  • dendritic cells
  • low grade
  • acute myeloid leukemia
  • smoking cessation
  • mesenchymal stem cells
  • high grade