A major genetic determinant of autoimmune diseases is associated with the presence of autoantibodies in hypersensitivity pneumonitis.
Ivette Buendía-RoldánLuis Santiago-RuizGloria Pérez-RubioMayra MejíaJorge Rojas-SerranoEnrique Ambrocio-OrtizGeovanni Benítez-ValdezMoisés SelmanRamcés Falfan-ValenciaPublished in: The European respiratory journal (2020)
A subset of hypersensitivity pneumonitis patients presents circulating autoantibodies and higher mortality that are associated with some alleles of 8.1 ancestral haplotype.
Keyphrases
- end stage renal disease
- systemic lupus erythematosus
- ejection fraction
- newly diagnosed
- chronic kidney disease
- drug induced
- prognostic factors
- peritoneal dialysis
- interstitial lung disease
- cardiovascular events
- type diabetes
- cardiovascular disease
- gene expression
- rheumatoid arthritis
- copy number
- patient reported outcomes
- dna methylation
- systemic sclerosis