Trichloroethylene and trichloroethanol induce skin sensitization with focal hepatic necrosis in guinea pigs.
Na ZhaoXiangrong SongHisao NaitoHongling LiYongshun HuangLili LiuFengrong LuTingfeng CaiYuki ItoMichihiro KamijimaHanlin HuangTamie NakajimaHailan WangPublished in: Journal of occupational health (2021)
TCE is the main cause of allergy and TCEOH is a secondary factor for allergy in guinea pigs. TCE and TCEOH can cause immune-mediated skin sensitization complicated by focal hepatic necrosis.