Application of 6-aminoquinolyl-N-hydroxysuccinimidyl carbamate derivatization for enhanced peptide mapping analysis of non-biological complex drug glatiramer acetate using liquid chromatography/electrospray ionization collision-induced dissociation high-resolution mass spectrometry.
Natalia V MesonzhnikRoman M KuznetsovNatalia L BochkarevaSvetlana A AppolonovaPublished in: Rapid communications in mass spectrometry : RCM (2021)
Application of the AQC pre-column derivatization provides a framework that could be used as an attractive approach for monitoring the quality and characterization of NBCD products in the pharmaceutical industry.
Keyphrases
- liquid chromatography
- high resolution mass spectrometry
- mass spectrometry
- tandem mass spectrometry
- ultra high performance liquid chromatography
- simultaneous determination
- gas chromatography
- high performance liquid chromatography
- solid phase extraction
- high resolution
- drug induced
- high glucose
- diabetic rats
- ms ms
- emergency department
- electron transfer