Formaldehyde effects on kanamycin resistance gene of inactivated recombinant Escherichia coli vaccines.

Rafael Amaral DonassoloMarcos Roberto A FerreiraClóvis MoreiraLucas M Dos SantosEmili GriepGustavo M S G MoreiraRafael R RodriguesÂngela N MoreiraFabricio R Conceição

Published in: Biotechnology letters (2020)

We found that this compound is effective as an inactivation agent. Here we demonstrate the biosafety involving antibiotic resistance gene of recombinant E. coli vaccines allowing to industrial production and animal application.

Keyphrases

escherichia coli
copy number
genome wide
genome wide identification
cell free
heavy metals
wastewater treatment
room temperature
risk assessment
klebsiella pneumoniae
biofilm formation
multidrug resistant
ionic liquid