Copper-Catalyzed Defluorinative Boroarylation of Alkenes with Polyfluoroarenes.

A catalytic defluorinative boroarylation of alkenes with polyfluoroarenes and B 2 pin 2 with the assistance of a PCy 3 -ligated copper catalyst was developed. Taking advantage of bench-stable alkenes as latent nucleophiles and avoiding traditional reliance on stoichiometric quantities of organometallics, this method showcased good functional group compatibility and proceeded under very mild reaction conditions. A series of valuable boronate-containing polyfluoroarenes including all-carbon quaternary carboncenter-containing triaryl alkylboronates that are otherwise difficult to access were efficiently prepared.