Association of glycated hemoglobin A1c levels with cardiovascular outcomes in the general population: results from the BiomarCaRE (Biomarker for Cardiovascular Risk Assessment in Europe) consortium.
Christoph R SinningNataliya MakarovaHenry VölzkeRenate B SchnabelFrancisco OjedaMarcus DörrStephan B FelixWolfgang KoenigAnnette PetersWolfgang RathmannBen SchöttkerHermann BrennerGiovanni VeronesiGiancarlo CesanaPaolo BrambillaTarja PalosaariKari KuulasmaaInger NjølstadEllisiv Bøgeberg MathiesenTom WilsgaardStefan BlankenbergStefan SöderbergMarco M FerrarioBarbara ThorandPublished in: Cardiovascular diabetology (2021)
HbA1c is independently associated with cardiovascular mortality, overall mortality and cardiovascular disease in the general European population. A mostly monotonically increasing relationship was observed between HbA1c levels and outcomes. Elevated HbA1c levels were associated with cardiovascular disease incidence and overall mortality in participants without diabetes underlining the importance of HbA1c levels in the overall population.