Effects of Ripasudil, a Rho-Kinase Inhibitor, on Scar Formation in a Mouse Model of Filtration Surgery.
Ji-Ae KoKaori KomatsuAkira MinamotoSatomi KondoHideaki OkumichiKazuyuki HirookaYoshiaki KiuchiPublished in: Current eye research (2023)
These results suggest that ripasudil, ROCK inhibitor may inhibit excessive fibrosis after glaucoma filtering surgery vis inhibition the transdifferentiation of tenon fibroblast into myofibroblast and may have a potential effect as anti-scarring for glaucoma filtration surgery.