Treatment of colitis by oral negatively charged nanostructured curcumin in rats.
Lívia Medeiros Soares CelaniEryvaldo Socrates Tabosa do EgitoÍtalo Medeiros AzevedoCláudia Nunes de OliveiraDouglas DouradoAldo da Cunha MedeirosPublished in: Acta cirurgica brasileira (2022)
The nanostructured microemulsion of curcumin, used orally, positively influenced the results of the treatment of UC in rats. The data also suggests that nanostructured curcumin with negative zeta potential is a promising phytopharmaceutical oral delivery system for UC therapy. Further research needs to be done to better understand the mechanisms of the negatively charged nanostructured curcumin microemulsion in UC therapy.