Myositis-specific autoantibodies and QTc changes by ECG in idiopathic inflammatory myopathies.

Sine Søndergaard KorsholmDaniel C AnderssonJohn Bonde KnudsenMaryam DastmalchiAxel C P DiederichsenOke GerkeNanna WittingSøren JacobsenRedi PeciniTina FriisMarkus E KrogagerIngrid E Lundberg Louise Pyndt Diederichsen

Published in: Rheumatology (Oxford, England) (2022)

The presence of QTc abnormalities was as common in patients with IIM as in patients with SSc, including prolonged QTc seen in almost one-fifth of the patients. Anti-Mi2, anti-Pl-7 and elevated CRP may serve as biomarkers for cardiac disease in IIM, but needs to be confirmed in a larger prospective study.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
peritoneal dialysis
prognostic factors
left ventricular
heart rate variability
patient reported outcomes
interstitial lung disease
systemic sclerosis
myasthenia gravis