Login / Signup

BODIPY as electron withdrawing group for the activation of double bonds in asymmetric cycloaddition reactions.

Andrea Guerrero-CorellaJuan Asenjo-PascualTushar Janardan PawarSergio Diaz-TenderoAna Martin-SomerClarisa Villegas GómezJosé L Belmonte-VázquezDiana E Ramírez-OrnelasEduardo Peña-CabreraAlberto FraileDavid Cruz CruzJosé Alemán
Published in: Chemical science (2019)
In this work we have found that a BODIPY can be used as an electron withdrawing group for the activation of double bonds in asymmetric catalysis. The synthesis of cyclohexyl derivatives containing a BODIPY unit can easily be achieved via trienamine catalysis. This allows a new different asymmetric synthesis of BODIPY derivatives and opens the door to future transformation of this useful fluorophore. In addition, the Quantum Chemistry calculations and mechanistic studies provide insights into the role of BODIPY as an EWG.
Keyphrases
  • fluorescent probe
  • living cells
  • molecular dynamics
  • single molecule
  • molecular dynamics simulations
  • solar cells
  • transition metal