Insulin and glucose homeostasis in childhood cancer survivors treated with abdominal radiation: A pilot study.
Danielle Novetsky FriedmanPatrick HildenChaya S MoskowitzSuzanne L WoldenEmily S TonorezosZoltan AntalDean CarlowShakeel ModakNai-Kong CheungKevin C OeffingerCharles A SklarPublished in: Pediatric blood & cancer (2018)
This study suggests that radiation-induced damage to the insulin-producing β-cells is an unlikely explanation for the early derangements in glucose metabolism observed after abdRT. Research into alternative pathways leading to diabetes after abdRT is needed.