Estimating the disutility of relapse in relapsing-remitting and secondary progressive multiple sclerosis using the EQ-5D-5L, AQoL-8D, EQ-5D-5L-psychosocial, and SF-6D: implications for health economic evaluation models.
Hasnat AhmadJulie A CampbellIngrid van der MeiBruce V TaylorQing XiaTing ZhaoAndrew J PalmerPublished in: Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation (2023)
MS-related relapses are associated with substantial utility decrements. As the type and severity of MS influence disutility of relapse, the use of disability severity and MS-type-specific disutility inputs is recommended in future health economic evaluations of MS. Our study supports relapse management and prevention as major mechanisms to improve QoL in people with MS.