Cancer-associated fibroblasts expressing fibroblast activation protein and podoplanin in non-small cell lung cancer predict poor clinical outcome.

Layla MathiesonLilian KoppensteinerDavid A DorwardRichard A O'ConnorAhsan R Akram

Published in: British journal of cancer (2024)

This study describes the fibroblast heterogeneity in NSCLC and the prognostic importance of the novel CAF-S5 subset where its presence correlates to worse survival outcome.

Keyphrases

small cell lung cancer
single cell
advanced non small cell lung cancer
extracellular matrix
protein protein
small molecule
wound healing
amino acid
binding protein
epidermal growth factor receptor