Clinical Significance of Exercise Pulmonary Hypertension With a Negative Diastolic Stress Test for Suspected Heart Failure With Preserved Ejection Fraction.
Jan VerwerftJan StassenMaarten FalterYouri BekhuisSarah HoedemakersTin GojevicSara Moura FerreiraSimon VanhentenrijkSarah StroobantsSiddharth JoganiDominique HansenRuta JasaityteBernard CosynsAlexander Van De BruaenePhilippe B BertrandRudolf A de BoerAndreas B GevaertFrederik Hendrik VerbruggeLieven HerbotsGuido ClaessenPublished in: Journal of the American Heart Association (2024)
Twenty-two percent of patients with suspected HFpEF presented with a mPAP/CO slope>3 mm Hg/L per min despite a negative DST. These patients had HFpEF characteristics and a peak oxygen uptake as low as patients with a positive DST. Therefore, an elevated mPAP/CO slope might indicate HFpEF irrespective of the DST result.