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Changes in neutrophile-to-lymphocyte ratio as predictive and prognostic biomarker in metastatic prostate cancer treated with taxane-based chemotherapy.

Manuel NeubergerChristel WeißNora GolyJanina SkladnyKatja NitschkeFrederik WesselsKarl F KowalewskiFrank WaldbilligFriedrich HartungMalin NientiedtLuisa EgenJonas HerrmannJonas JarczykMargarete Teresa WalachMaximilian C KriegmairNiklas WesthoffThomas S WorstPhilipp Nuhn
Published in: Discover. Oncology (2022)
This study demonstrated NLR3 as a prognostic marker in men receiving docetaxel for mCRPC. NLR3 might be a clinical tool to reflect the individual's response to taxane-based chemotherapy. Thereby, NLR3 could complement existing biomarkers and help to early identify treatment failure before complications arise. Further prospective and multicentric studies are needed to extend and confirm the presented results.
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