The involvement of epidermal growth factor receptor/protein kinase B signaling in the tumor intrinsic PD-L1-induced malignant potential of oral squamous cell carcinoma.

Eri SasabeAyumi TomomuraTetsuya Yamamoto

Published in: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology (2024)

OSCC cells-expressing PD-L1 induced by EGF stimulation may promote malignancy intrinsically via the activation of the EGFR/AKT signaling cascade.

Keyphrases

epidermal growth factor receptor
tyrosine kinase
advanced non small cell lung cancer
induced apoptosis
protein kinase
signaling pathway
cell cycle arrest
small cell lung cancer
cell proliferation
high glucose
growth factor
diabetic rats
cell death