Acetylsalicylic acid rescues the immunomodulation of inflamed gingiva-derived mesenchymal stem cells via upregulating FasL in mice.

Tingting YuBoxi YanJing LiTing ZhangRuili YangXuedong WangYan LiuYu Shrike Zhang

Published in: Stem cell research & therapy (2019)

This study indicates that the deficient immunomodulatory function of iGMSCs could be rescued by ASA pretreatment via upregulating of FasL in mice. This strategy might serve as a practical approach to rescue deficient MSC function for further therapeutic application.

Keyphrases

wild type
high fat diet induced
insulin resistance
metabolic syndrome