Imperatorin interacts additively with novel antiseizure medications in the mouse maximal electroshock-induced seizure model: an isobolographic transformation.

Jarogniew J LuszczkiEwelina Kochman-MoskalHubert Bojar Magdalena Florek-Łuszczki Krystyna Skalicka Woźniak

Published in: Pharmacological reports : PR (2023)

The additive interactions of IMP with LCM, OXC, PGB, and TPM in the mouse MES model accompanied by no pharmacokinetic changes in the total brain content of ASMs are worthy of recommendation for further studies.

Keyphrases

white matter
diabetic rats
heart rate
oxidative stress
binding protein
drug induced
multiple sclerosis
body composition
case control