Association of pre-existing comorbidities with mortality and disease severity among 167,500 individuals with COVID-19 in Canada: A population-based cohort study.
Erjia GeYanhong LiShishi WuElisa CandidoXiaolin WeiPublished in: PloS one (2021)
We found that solid organ transplant, dementia, chronic kidney disease, severe mental illness, CVD, hypertension, COPD, cancer, diabetes, rheumatoid arthritis, HIV, and asthma were associated with mortality or severity. Our study highlights that the number of comorbidities was a strong risk factor for deaths and severe outcomes among younger individuals with COVID-19. Our findings suggest that in addition of prioritizing by age, vaccination priority groups should also include younger population with multiple comorbidities.
Keyphrases
- mental illness
- coronavirus disease
- sars cov
- chronic kidney disease
- rheumatoid arthritis
- chronic obstructive pulmonary disease
- lung function
- cardiovascular events
- mental health
- type diabetes
- early onset
- cardiovascular disease
- blood pressure
- antiretroviral therapy
- human immunodeficiency virus
- end stage renal disease
- hiv positive
- mild cognitive impairment
- hiv infected
- hepatitis c virus
- risk factors
- cognitive impairment
- hiv aids
- respiratory syndrome coronavirus
- squamous cell
- hiv testing
- disease activity
- drug induced
- squamous cell carcinoma
- air pollution
- systemic lupus erythematosus
- adipose tissue
- coronary artery disease
- insulin resistance
- young adults
- arterial hypertension