Soluble Programmed Cell Death Protein 1 and Its Ligand: Potential Biomarkers to Predict Acute Kidney Injury After Surgery in Critically Ill Patients.

Jingyi WangXi ZhengYijia JiangHuimiao JiaXiaocui ShiYue HanQingping LiWenxiong Li

Published in: Journal of inflammation research (2022)

The increased expressions of PD-1 and PD-L1 in kidneys under IRI suggested they may play essential roles in AKI development. sPD-1 and sPD-L1 can indirectly reflect the expressions of PD-1 and PD-L1 in kidneys, respectively. sPD-1 and sPD-L1 showed excellent predictive ability for AKI in high-risk patients.

Keyphrases

acute kidney injury
cardiac surgery
end stage renal disease
newly diagnosed
peritoneal dialysis
patient reported outcomes
binding protein
patient reported