The Role of Serum Monocytes and Tissue Macrophages in Driving Left Ventricular Systolic Dysfunction and Cardiac Inflammation Following Subarachnoid Hemorrhage.
Joseph R GeraghtyNeil S SainiAshwini DeshpandeTiffany ChengNoreen NazirFernando D TestaiPublished in: Neurocritical care (2023)
Increased serum leukocytes are associated with abnormal left ventricular systolic function following aSAH. The strongest independent predictor of both reduced and hyperdynamic systolic function was increased monocytes. Increased cardiac macrophages after experimental SAH can also be targeted by using immunomodulatory drugs.
Keyphrases
- left ventricular
- subarachnoid hemorrhage
- hypertrophic cardiomyopathy
- heart failure
- cardiac resynchronization therapy
- brain injury
- acute myocardial infarction
- aortic stenosis
- mitral valve
- left atrial
- peripheral blood
- oxidative stress
- cerebral ischemia
- blood pressure
- dendritic cells
- cancer therapy
- acute coronary syndrome
- coronary artery disease
- aortic valve