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Reactive oxygen species generation required for autophagy induction during butyrate- or propionate-induced release of damage-associated molecular patterns from dying gingival epithelial Ca9-22 cells.

Kiwa MiyakeYoshikazu MikamiTakayuki AsayamaTaku ToriumiKeiji ShinozukaMorio TonogiYoshiyuki YoneharaHiromasa Tsuda
Published in: Journal of oral science (2024)
The findings suggest that ROS generation is necessary for autophagy, which is required for SCFA-induced cell death and accompanying DAMP release.
Keyphrases
  • cell death
  • cell cycle arrest
  • reactive oxygen species
  • oxidative stress
  • diabetic rats
  • high glucose
  • induced apoptosis
  • endoplasmic reticulum stress
  • palliative care
  • drug induced
  • cell proliferation