Synthetic extracellular matrices and astrocytes provide a supportive microenvironment for the cultivation and investigation of primary pediatric gliomas.
Christopher M RotaAlexander T BrownEmily AddlesonClara IvesElla TrumperKristine PeltonWei Pin TehMatthew J SchniederjanRobert Craig CastellinoSara BuhrlageDouglas A LauffenburgerKeith L LigonLinda G GriffithRosalind A SegalPublished in: Neuro-oncology advances (2022)
Our sECM culture platform provides a multipurpose tool for pediatric brain tumor researchers that enables both a wide breadth of biological assays and the cultivation of diverse tumor types.
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