Combined targeting of HER-2 and HER-3 represents a promising therapeutic strategy in colorectal cancer.
Lena-Christin ConradiMelanie SpitznerAnna-Lena MetzgerMerle KislyPeter MiddelHanibal BohnenbergerJochen GaedckeMichael B GhadimiTorsten LierschJoseph RüschoffTim BeißbarthAlexander KönigMarian GradePublished in: BMC cancer (2019)
Since HER-2 and HER-3 are expressed in a relevant number of patients, targeting both receptors may represent a promising therapeutic strategy for CRC.