Extracellular Vesicles Propagate Lung Fibrosis in Systemic Sclerosis.
Joe E MouawadMatthew SandersonShailza SharmaKristi L HelkeJoseph M PilewskiSatish N NadigCarol A Feghali-BostwickPublished in: Arthritis & rheumatology (Hoboken, N.J.) (2023)
Our findings highlight EV communication as a novel mechanism for propagation of SSc lung fibrosis. Identifying therapies that reduce EV release, activity, and/or fibrotic cargo in SSc patient lungs may be a viable therapeutic strategy to improve fibrosis. This article is protected by copyright. All rights reserved.