Peripheral Immune Cell Populations Associated with Cognitive Deficits and Negative Symptoms of Treatment-Resistant Schizophrenia.

Emilio Fernandez-EgeaPetra E VértesShaun M FlintLorinda TurnerSyed MustafaAlex HattonKenneth G C SmithPaul A LyonsEdward T Bullmore

Published in: PloS one (2016)

Peripheral immune cell populations and dopaminergic signalling are disrupted in clozapine-treated schizophrenia. Immuno-phenotypes may provide peripherally accessible and mechanistically specific biomarkers of residual cognitive and negative symptoms in this treatment-resistant subgroup of patients.

Keyphrases

bipolar disorder
end stage renal disease
newly diagnosed
ejection fraction
chronic kidney disease
prognostic factors
peritoneal dialysis
clinical trial
physical activity
study protocol