Precise prostate cancer diagnosis using fluorescent nanoprobes for detecting PSA and PSMA in serum.
Mingyi OuyangMing JiaZixuan ChangYinian WangKeyi WangXiaonan GaoBo TangPublished in: Chemical communications (Cambridge, England) (2024)
Novel Au-Se bond-based nanoprobes were designed for concurrent detection of PSA and PSMA in serum samples, aiming to enhance the early diagnosis of prostate cancer. These probes demonstrate robust stability, specificity and accuracy, underscoring their potential as non-invasive tools for diagnosis.
Keyphrases
- prostate cancer
- radical prostatectomy
- pet ct
- fluorescence imaging
- pet imaging
- living cells
- small molecule
- label free
- quantum dots
- sensitive detection
- photodynamic therapy
- loop mediated isothermal amplification
- locally advanced
- risk assessment
- computed tomography
- gold nanoparticles
- radiation therapy
- positron emission tomography
- real time pcr
- transition metal
- solid state