Liposomes are well-recognized and essential nano-sized drug delivery systems. Liposomes are phospholipid vesicles comprised of cell membrane components and have been employed as artificial cell models to mimic structure and functions of cells and are of immense use in various biological analyses. Liposomes acquire great advantages and provide wide range of applications as useful drug carriers in pre-clinical and clinical trials. This review summarizes exclusively on scalable techniques for liposome preparation and focuses on the strengths and limitations with respect to industrial applicability. Also, this review discusses the updated recent advancements in biomedical applications with a mention of key highlights of commercially available formulations, clinical trials and patents in recent past. Furthermore, this review also provides brief information of the classification, composition and characterization of liposomes.
Keyphrases
- clinical trial
- drug delivery
- drug release
- induced apoptosis
- risk assessment
- healthcare
- deep learning
- cell therapy
- emergency department
- open label
- study protocol
- oxidative stress
- high resolution
- cell cycle arrest
- cell proliferation
- signaling pathway
- social media
- mesenchymal stem cells
- endoplasmic reticulum stress
- adverse drug