Both Granulocytic and Non-Granulocytic Blood Cells Are Affected in Patients with Severe Congenital Neutropenia and Their Non-Neutropenic Family Members: An Evaluation of Morphology, Function, and Cell Death
Lale OlcayŞule ÜnalHüseyin OnayEsra ErdemliAyşenur ÖztürkDeniz BillurAyse MetinHamza OkurZeynep Yildiz YildirmakYahya BuyukasikAydan İkincioğullarıMesude FalayGülsüm ÖzetSevgi YetginPublished in: Turkish journal of haematology : official journal of Turkish Society of Haematology (2018)
In cases of SCN, patients’ pluripotent hematopoietic stem cells and their non-neutropenic parents are both affected irrespective of the genetic defect.
Keyphrases
- stem cells
- cell death
- end stage renal disease
- cell cycle arrest
- ejection fraction
- chronic kidney disease
- newly diagnosed
- induced apoptosis
- bone marrow
- peritoneal dialysis
- early onset
- gene expression
- genome wide
- copy number
- oxidative stress
- patient reported outcomes
- mesenchymal stem cells
- endoplasmic reticulum stress
- chemotherapy induced