Prognostic significance of the neural invasion in oral squamous cell carcinoma.
Eder Silva da DolensEverton Freitas de MoraisLívia Máris Ribeiro ParanaíbaAna Lúcia Carrinho Ayroza RangelAlhadi AlmangushTuula Anneli SaloPeter A BrennanRicardo Della ColettaPublished in: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology (2023)
This study provides evidence that intraneural invasion, but not perineural invasion, is a relevant predictor of survival in patients with oral squamous cell carcinomas, suggesting that its association with other clinical and pathological prognostic factors should be consider in determining the optimal treatment protocol and prognosis of these patients.