Astragaloside IV Reduces Cerebral Ischemia/Reperfusion-Induced Blood-Brain Barrier Permeability in Rats by Inhibiting ER Stress-Mediated Apoptosis.

Published in: Evidence-based complementary and alternative medicine : eCAM (2020)

AS-IV can effectively protect the blood-brain barrier and reduce the area of cerebral infarction via inhibiting endoplasmic reticulum stress-mediated apoptosis in endothelial cells.

Keyphrases

blood brain barrier
endoplasmic reticulum stress
endothelial cells
high glucose
induced apoptosis
cerebral ischemia
signaling pathway
diabetic rats
subarachnoid hemorrhage
vascular endothelial growth factor
oxidative stress
drug induced
cerebral blood flow