Efficacy of laser interstitial thermal therapy for biopsy-proven radiation necrosis in radiographically recurrent brain metastases.
Michael D ChanSteven TatterVeronica ChiangPeter FecciRoy StrowdSujit PrabhuConstantinos HadjipanayisJohn KirkpatrickDavid SunKaylyn SinicropeAlireza M MohammadiParag SevakSteven AbramAlbert H KimEric LeuthardtSamuel ChaoJohn PhillipsMichel LacroixBrian WilliamsDimitris PlacantonakisJoshua SilvermanJames BaumgartnerDavid PiccioniAdrian LaxtonPublished in: Neuro-oncology advances (2023)
LITT for RN was not only again found to be safe with low patient morbidity but was also a highly effective treatment for RN for both local control and symptom management (including seizures). In addition to averting expected neurological death, LITT facilitates ongoing systemic therapy (in particular immunotherapy) by enabling the rapid cessation of steroids, thereby facilitating maximal possible survival for these patients.
Keyphrases
- brain metastases
- small cell lung cancer
- end stage renal disease
- ejection fraction
- newly diagnosed
- prognostic factors
- stem cells
- patient reported
- radiation induced
- blood brain barrier
- combination therapy
- bone marrow
- replacement therapy
- smoking cessation
- radiation therapy
- resistance training
- mesenchymal stem cells
- cerebral ischemia
- drug induced
- high intensity
- high resolution