CCKR signaling map, G-Protein bindings, hormonal regulation, and neural mechanisms may influence the osteogenic/cementogenic differentiation potential of hPDLSCs.
Catharina Marques SacramentoMiki Taketomi SaitoMárcio Zaffalon CasatiEnilson Antonio SallumRenato Correa Viana CasarinKarina Gonzales SilvérioPublished in: Archives of oral biology (2024)
The osteo/cementogenic differentiation of HOP cells may be regulated by CCKR signaling, G-protein bindings, and specific hormonal regulation. LOP cells seem committed to neural mechanisms. This study sheds light on hPDLSCs' complex characteristics, offering a deeper understanding of their differentiation potential for future periodontal regeneration research and therapies.