In Situ Generation of Ruthenium Carbonyl Phosphine Complexes as a Versatile Method for the Development of Enantioselective C-O Bond Arylation.

Hikaru KondoTakuya Kochi Fumitoshi Kakiuchi

Published in: Chemistry (Weinheim an der Bergstrasse, Germany) (2020)

We report here a method for in situ generation of various ruthenium carbonyl phosphine catalysts for arylation via cleavage of inert aromatic carbon-oxygen bonds. The use of catalyst systems consisting of [RuCl2 (CO)(p-cymene)], CsF, styrene, and phosphines enabled facile screening of phosphine ligands. Asymmetric C-O arylation was also achieved for atropo-enantioselective biaryl synthesis using a chiral monodentate phosphine ligand.

Keyphrases

highly efficient
metal organic framework
ionic liquid
reduced graphene oxide
transition metal
quantum dots
amino acid
carbon dioxide