Maternal host responses to poly(I:C) during pregnancy leads to both dysfunctional immune profiles and altered behaviour in the offspring.

Pablo Garcia-ValtanenBianca A van DiermenNerissa LakhanErin L LousbergSarah A RobertsonJohn D HayballKerrilyn R Diener

Published in: American journal of reproductive immunology (New York, N.Y. : 1989) (2020)

MIA induced by pathogens during pregnancy can interfere with the development of the foetal immune and nervous systems leading to dysfunctional immune responses and behaviour in offspring.

Keyphrases

immune response
high fat diet
birth weight
gram negative
metabolic syndrome
skeletal muscle
pregnant women
inflammatory response
preterm birth