Production and Characterization of Two Specific ZIKV Antigens Based on Bioinformatic Analysis and Serological Screening.

Rafael Ribeiro Mota Souza Gubio Soares Campos Rejane H CarvalhoIsabela Brandão PeixotoRafaela Santos GalanteLuan Santana MoreiraSilvana Beutinger Marchioro Roberto José Meyer Nascimento Silvia Ines Sardi

Published in: Immunological investigations (2023)

These findings demonstrate that ZIKV NS1 fraction 220-352 is a potential tool that may be applied in the development of serological diagnosis. We also provided data that suggest the non-applicability of the region 146-182 of ZIKV's protein E in serological assays despite previous indications about its potential based on computational analysis.

Keyphrases

zika virus
dendritic cells
dengue virus
deep learning
electronic health record
big data
protein protein