Genome-wide analysis of DNA methylation in Hirschsprung enteric precursor cells: unraveling the epigenetic landscape of enteric nervous system development.

Leticia Villalba-BenitoDaniel López-LópezAna TorroglosaCarlos S Casimiro-SoriguerBerta Luzón-ToroRaquel María FernándezMaría José Moya-JiménezGuillermo AntiñoloJoaquín DopazoSalud Borrego

Published in: Clinical epigenetics (2021)

This study highlights the relevance of an adequate methylation pattern for a proper ENS development. This is a research area that provides a novel approach to deepen our understanding of the etiopathogenesis of HSCR.

Keyphrases

dna methylation
genome wide analysis
genome wide
induced apoptosis
gene expression
cell cycle arrest
single cell
cell death
pi k akt