Proteomic and Transcriptomic Analysis Identify Spliceosome as a Significant Component of the Molecular Machinery in the Pituitary Tumors Derived from POU1F1- and NR5A1-Cell Lineages.
Keiko Taniguchi-PoncianoEduardo Peña-MartínezGloria Silva-RománSandra Vela-PatiñoAna Laura Guzman-OrtizHéctor QuezadaErick Gomez-ApoLaura Chavez-MaciasSophia Mercado-MedrezGuadalupe Vargas-OrtegaAna Laura Espinosa-de-Los-MonterosBaldomero Gonzales-VirlaAldo Ferreira-HermosilloEtual Espinosa-CardenasClaudia Ramirez-RenteriaErnesto Sosa-ErozaBlas Lopez-FelixGerardo GuintoDaniel Marrero-RodríguezMoises MercadoPublished in: Genes (2020)
Spliceosome components are significant constituents of the PA molecular machinery and could be used as molecular markers and therapeutic targets. Splicing-related genes and mRNA-isoforms profiles characterize tumor subtypes.