Inactivated genotype 1a, 2a and 3a HCV vaccine candidates induced broadly neutralising antibodies in mice.
Garazi Pena AlzuaAnne Finne PihlAnna OffersgaardCarlos Rene Duarte HernandezZhe DuanShan FengUlrik FahnøeChristina SølundNina WeisMansun LawJannick C PrentoeJan Pravsgaard ChristensenJens BukhJudith Margarete GottweinPublished in: Gut (2022)
High-yield genotype 1-3 HCV could be developed as basis for inactivated vaccine candidates inducing broadly neutralising antibodies in mice supporting further preclinical development.