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LAP2α preserves genome integrity through assisting RPA deposition on damaged chromatin.

Kaiwen BaoQi ZhangShuai LiuNan SongQiushi GuoLing LiuShanshan TianJihui HaoYi ZhuKai ZhangDing AiJie YangZhi YaoRoland FoisnerLei Shi
Published in: Genome biology (2022)
Our study provides mechanistic insight into RPA deposition in response to DNA damage and reveals a genome protection role of LAP2α.
Keyphrases
  • dna damage
  • genome wide
  • oxidative stress
  • gene expression
  • dna repair
  • dna methylation