A 4-month-old infant presented with continued fever, unresolving bronchopneumonia and household contact with sputum-smear-positive tuberculosis (TB) and showed marginal improvement on anti-TB chemotherapy. Recurrent pneumothorax prompted the clinical diagnosis of TB to be revised. High-resolution CT scan of the chest and open lung biopsy confirmed the diagnosis of pulmonary Langerhans cell histiocytosis. Treatment with prednisolone and vinblastin resulted in settling of fever and resolution of respiratory symptoms and signs. In communities where the prevalence of TB is high, unusual presentations should prompt consideration of alternative diagnoses.
Keyphrases
- mycobacterium tuberculosis
- pulmonary tuberculosis
- high resolution
- single cell
- pulmonary hypertension
- computed tomography
- cell therapy
- risk factors
- minimally invasive
- squamous cell carcinoma
- dual energy
- hiv aids
- cystic fibrosis
- single molecule
- emergency department
- magnetic resonance
- mesenchymal stem cells
- positron emission tomography
- sleep quality
- adverse drug
- smoking cessation