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Umbilical cord as a long-term source of activatable mesenchymal stromal cells for immunomodulation.

Anton SelichKatharina ZimmermannMichel TenspoldeOliver Dittrich-BreiholzConstantin von KaisenbergAxel SchambachMichael Rothe
Published in: Stem cell research & therapy (2019)
Human umbilical cord maintains a microenvironment for the long-term induction of polyclonal and immune inhibitory active MSCs for months. Thus, our results would offer the possibility to drastically increase the number of therapeutically applicable MSCs for a substantial amount of patients.
Keyphrases
  • umbilical cord
  • mesenchymal stem cells
  • bone marrow
  • end stage renal disease
  • ejection fraction
  • newly diagnosed
  • endothelial cells
  • chronic kidney disease
  • stem cells
  • peritoneal dialysis
  • prognostic factors