Reconstruction of 3D Chromosome Structure from Single-Cell Hi-C Data via Recurrence Plots.

Yoshito HirataHiroki SugishitaYukiko Gotoh

Published in: Methods in molecular biology (Clifton, N.J.) (2024)

We describe an approach for reconstructing three-dimensional (3D) structures from single-cell Hi-C data. This approach has been inspired by a method of recurrence plots and visualization tools for nonlinear time series data. Some examples are also presented.

Keyphrases

single cell
electronic health record
rna seq
big data
high throughput
high resolution
gene expression
machine learning
mass spectrometry